Semaglutide Dosing Calculator
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Semaglutide Dosing Calculator
Calculated Next Step
Enter details to calculate.
Understanding Semaglutide Dosing
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist increasingly prescribed for the management of Type 2 Diabetes and chronic weight management (obesity/overweight with comorbidities). Dosing is typically started low and gradually increased to improve tolerability and achieve therapeutic efficacy. This calculator provides an estimate for the next potential dose based on common titration schedules, but it is not a substitute for professional medical advice. Always consult with your healthcare provider for personalized dosing recommendations.
Standard Titration Schedules
The escalation of semaglutide dosage usually follows a structured pattern, with dose increases occurring every few weeks or months, depending on patient tolerance and treatment goals. The most common target doses for Type 2 Diabetes are 1.0 mg and 2.0 mg weekly, while for weight management, the target dose is often 2.4 mg weekly.
- Type 2 Diabetes: Common titration involves increasing the dose every 4 weeks. Starting doses are typically 0.25 mg, then progressing through 0.5 mg, 1.0 mg, and finally reaching a maintenance dose of 2.0 mg.
- Obesity/Overweight: The titration schedule for weight management often follows a similar pattern but may aim for a higher maximum dose of 2.4 mg. Increases are also typically made every 4 weeks.
How This Calculator Works
This calculator uses a simplified logic based on typical clinical practice for semaglutide titration.
- Indication: Selects the primary use case (Type 2 Diabetes or Obesity), which influences the potential maximum dose.
- Current Dose (mg): The dose the patient is currently taking.
- Weeks Since Last Dose Increase: A key factor in determining when the next dose increase might be appropriate. Standard practice often involves waiting at least 4 weeks (or more) before increasing the dose to assess tolerability and efficacy.
- Target Dose (mg): The intended final or maximum dose for the patient's condition.
The calculator will suggest the next logical dose increase if the patient has been on the current dose for a sufficient duration (typically 4 weeks or more) and has not yet reached their target dose. It considers standard step-up increments (e.g., from 0.5 mg to 1.0 mg, or 1.0 mg to 2.0 mg).
Important Considerations:
- Tolerability: The most crucial factor is patient tolerance. Gastrointestinal side effects (nausea, vomiting, diarrhea) are common, especially during dose escalation. If side effects are significant, the dose increase may need to be delayed or the dose reduced.
- Individual Response: Patients respond differently to medications. Some may require slower titration, while others may tolerate faster increases.
- Medical Supervision: This tool is for informational purposes only. Semaglutide is a prescription medication, and its use and dosage must be determined and monitored by a qualified healthcare professional.
- Maximum Doses: For Type 2 Diabetes, 2.0 mg weekly is a common maximum. For obesity, 2.4 mg weekly is the approved maximum dose.
Disclaimer: This calculator does not provide medical advice. It is intended for educational and informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition or treatment. Never disregard professional medical advice or delay in seeking it because of something you have read on this website.
function calculateDose() {
var indication = document.getElementById("indication").value;
var currentDoseMg = parseFloat(document.getElementById("currentDoseMg").value);
var durationSinceLastIncrease = parseInt(document.getElementById("durationSinceLastIncrease").value);
var targetDoseMg = parseFloat(document.getElementById("targetDoseMg").value);
var resultDiv = document.getElementById("result");
// Clear previous results and error messages
resultDiv.innerHTML = "";
resultDiv.style.backgroundColor = "var(–success-green)"; // Reset background
// Input validation
if (isNaN(currentDoseMg) || isNaN(durationSinceLastIncrease) || isNaN(targetDoseMg)) {
resultDiv.innerHTML = "Please enter valid numbers for all fields.";
resultDiv.style.backgroundColor = "#dc3545"; // Error color
return;
}
if (currentDoseMg < 0 || durationSinceLastIncrease < 0 || targetDoseMg = targetDoseMg) {
resultDiv.innerHTML = "Current dose is already at or above the target dose.";
resultDiv.style.backgroundColor = "#ffc107"; // Warning color
return;
}
var nextDose = null;
var commonIncrements = [0.25, 0.5, 1.0, 1.7]; // Typical increments towards 2.4mg
var diabetesIncrements = [0.25, 0.5, 1.0]; // Typical increments towards 2.0mg
var possibleNextDose = currentDoseMg;
// Logic for determining the next dose step
if (indication === "type2diabetes") {
if (currentDoseMg = 4) possibleNextDose = 0.5;
else if (currentDoseMg = 4) possibleNextDose = 1.0;
else if (currentDoseMg = 4) possibleNextDose = 2.0;
else if (durationSinceLastIncrease targetDoseMg) {
possibleNextDose = targetDoseMg;
}
if (possibleNextDose === currentDoseMg && currentDoseMg < targetDoseMg) {
resultDiv.innerHTML = "No standard dose increase at this level. Consult your doctor.";
resultDiv.style.backgroundColor = "#ffc107"; // Warning color
return;
}
nextDose = possibleNextDose;
} else if (indication === "obesity") {
if (currentDoseMg = 4) possibleNextDose = 0.5;
else if (currentDoseMg = 4) possibleNextDose = 1.0;
else if (currentDoseMg = 4) possibleNextDose = 1.7; // Common step towards 2.4mg
else if (currentDoseMg = 4) possibleNextDose = 2.4;
else if (durationSinceLastIncrease targetDoseMg) {
possibleNextDose = targetDoseMg;
}
if (possibleNextDose === currentDoseMg && currentDoseMg < targetDoseMg) {
resultDiv.innerHTML = "No standard dose increase at this level. Consult your doctor.";
resultDiv.style.backgroundColor = "#ffc107"; // Warning color
return;
}
nextDose = possibleNextDose;
}
if (nextDose !== null) {
resultDiv.innerHTML = "Recommended Next Dose:
" + nextDose.toFixed(2) + " mg";
if (nextDose === targetDoseMg) {
resultDiv.innerHTML += "(Reached Target Dose)";
}
} else {
resultDiv.innerHTML = "Cannot calculate next dose based on inputs. Consult your doctor.";
resultDiv.style.backgroundColor = "#dc3545"; // Error color
}
}