Frozen Embryo Transfer Success Rate Calculator

Frozen Embryo Transfer (FET) Success Rate Calculator

Unexplained Infertility PCOS Endometriosis Male Factor Infertility Tubal Factor Infertility
function calculateFETSuccessRate() { var age = parseFloat(document.getElementById("age").value); var embryoQuality = parseFloat(document.getElementById("embryoQuality").value); var previousPregnancies = parseFloat(document.getElementById("previousPregnancies").value); var uterineLining = parseFloat(document.getElementById("uterineLining").value); var fertilityDiagnosis = document.getElementById("fertilityDiagnosis").value; var resultDiv = document.getElementById("result"); if (isNaN(age) || isNaN(embryoQuality) || isNaN(previousPregnancies) || isNaN(uterineLining)) { resultDiv.innerHTML = "Please enter valid numbers for all inputs."; return; } if (age 50 || embryoQuality 5 || previousPregnancies 1 || uterineLining 20) { resultDiv.innerHTML = "Please ensure all input values are within the acceptable ranges."; return; } // This is a simplified model. Actual FET success rates are complex and influenced by many factors. // These weights are illustrative and not based on specific clinical data. var baseRate = 0.4; // Base success rate (40%) // Adjustments based on factors var ageAdjustment = 0; if (age = 30 && age = 35 && age < 40) { ageAdjustment = -0.1; } else { ageAdjustment = -0.2; } var qualityAdjustment = (embryoQuality – 3) * 0.05; // Higher quality, higher rate var previousPregnancyAdjustment = (previousPregnancies === 1) ? 0.05 : 0; // Slight boost for prior success var liningAdjustment = (uterineLining – 10) * 0.01; // Optimal lining thickness is around 10-12mm var diagnosisAdjustment = 0; switch (fertilityDiagnosis) { case "unexplained": diagnosisAdjustment = 0; break; case "pcos": diagnosisAdjustment = 0.02; break; case "endometriosis": diagnosisAdjustment = -0.05; break; case "maleFactor": diagnosisAdjustment = 0.03; break; case "tubalFactor": diagnosisAdjustment = -0.07; break; } var calculatedRate = baseRate + ageAdjustment + qualityAdjustment + previousPregnancyAdjustment + liningAdjustment + diagnosisAdjustment; // Ensure the rate is within a plausible range (e.g., 0% to 100%) calculatedRate = Math.max(0, Math.min(1, calculatedRate)); var successPercentage = (calculatedRate * 100).toFixed(2); resultDiv.innerHTML = "Estimated FET Success Rate: " + successPercentage + "%"; } .calculator-container { font-family: sans-serif; border: 1px solid #ccc; padding: 20px; border-radius: 8px; max-width: 500px; margin: 20px auto; background-color: #f9f9f9; } .calculator-title { text-align: center; color: #333; margin-bottom: 20px; } .calculator-inputs { display: grid; grid-template-columns: 1fr; gap: 15px; } .input-group { display: flex; flex-direction: column; } .input-group label { margin-bottom: 5px; font-weight: bold; color: #555; } .input-group input, .input-group select { padding: 10px; border: 1px solid #ccc; border-radius: 4px; font-size: 1rem; } .calculator-button { display: block; width: 100%; padding: 12px 20px; background-color: #007bff; color: white; border: none; border-radius: 4px; font-size: 1.1rem; cursor: pointer; margin-top: 20px; transition: background-color 0.3s ease; } .calculator-button:hover { background-color: #0056b3; } .calculator-result { margin-top: 25px; padding: 15px; border: 1px dashed #007bff; background-color: #e7f3ff; border-radius: 4px; text-align: center; font-size: 1.2rem; color: #0056b3; } .calculator-result p { margin: 0; } .calculator-result strong { font-size: 1.4rem; }

Understanding Frozen Embryo Transfer (FET) Success Rates

A Frozen Embryo Transfer (FET) is a crucial part of assisted reproductive technology (ART), involving the transfer of a previously frozen embryo into the uterus. The success of an FET cycle is influenced by a multitude of factors, and while no calculator can predict outcomes with certainty, understanding these variables can provide a clearer picture of potential success. This calculator offers an *estimated* success rate based on several key inputs, but it is essential to remember that individual results can vary significantly.

Factors Influencing FET Success:

Maternal Age:

Age is one of the most significant determinants of reproductive success. As women age, the quality and quantity of their eggs decline, directly impacting embryo viability and the likelihood of a successful pregnancy. Younger women generally have higher success rates.

Embryo Quality:

The quality of the embryo transferred plays a pivotal role. Embryos are graded based on their morphological characteristics (like cell division rate and fragmentation) and developmental stage. Higher quality embryos (e.g., blastocysts with good grades) have a greater potential to implant and result in a live birth.

Previous Successful Pregnancies:

Having had a previous successful pregnancy can sometimes indicate a higher likelihood of future success, as it suggests a certain reproductive capability. However, this is not always a definitive factor.

Uterine Lining Thickness:

The endometrium, or uterine lining, must be adequately thick and receptive for an embryo to implant successfully. A well-prepared uterine lining, typically between 7mm and 12mm or more, is crucial. Insufficient thickness can hinder implantation.

Fertility Diagnosis:

The underlying cause of infertility can impact FET success rates. For instance, conditions like endometriosis or tubal factor infertility might present different challenges compared to male factor infertility or unexplained infertility. The specific diagnosis can influence the implantation potential.

How the Calculator Works:

This calculator uses a simplified algorithm that assigns a base success rate and then adjusts it based on the inputs provided. Each factor is assigned a potential positive or negative impact on the overall probability. For example, younger maternal age, higher embryo quality, and an optimally thick uterine lining are generally associated with increased success probabilities, while certain fertility diagnoses might slightly decrease the estimated rate.

Disclaimer: This calculator is intended for educational purposes only and should not be considered medical advice. It provides a general estimation and does not guarantee any specific outcome. Always consult with your fertility specialist for personalized advice and to discuss your individual situation and prognosis.

Example Calculation:

Let's consider a 32-year-old woman undergoing an FET. She has a good quality embryo (score 4 out of 5), has had a previous successful pregnancy, has a uterine lining thickness of 11mm, and her fertility diagnosis is PCOS.

Based on these inputs, the calculator might estimate a success rate that reflects the favorable aspects of her age, embryo quality, previous pregnancy history, and uterine lining, while considering the specific influence of PCOS. This scenario would likely yield a higher estimated success rate than if she were older or had a lower embryo quality.

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