Glucose Infusion Rate (GIR) Calculator
Enter 10 for D10W, 12.5 for D12.5W, etc.
Please enter valid positive numbers for all fields.
Glucose Infusion Rate (GIR)
— mg/kg/min
Total Daily Fluid Volume
— mL/kg/day
Daily Glucose Load
— g/day
About the Glucose Infusion Rate Calculator
This Glucose Infusion Rate (GIR) calculator allows clinicians, nurses, and medical professionals to quickly determine the amount of glucose a patient is receiving per minute, normalized by body weight. This calculation is particularly critical in neonatal intensive care units (NICU) and pediatric settings to ensure infants maintain euglycemia (normal blood sugar levels).
How to Calculate GIR
The calculation determines the rate at which glucose is delivered in milligrams per kilogram of body weight per minute (mg/kg/min). The standard formula used is:
GIR = (Rate × Concentration) ÷ (6 × Weight)
Where:
- Rate = IV Infusion Rate in mL/hour
- Concentration = Percentage of Dextrose (e.g., 10 for D10)
- Weight = Patient's weight in kg
- 6 = A conversion factor derived from converting mL/hr to mg/min
Why Monitoring GIR is Critical
Maintaining proper glucose homeostasis is vital for brain function and development, especially in neonates.
- Hypoglycemia (Low GIR): Insufficient glucose delivery can lead to lethargy, seizures, and potential neurological damage.
- Hyperglycemia (High GIR): Excessive glucose can cause osmotic diuresis, dehydration, and increased risk of intraventricular hemorrhage in preterm infants.
Typical GIR Ranges
While target ranges vary based on clinical protocols and the patient's specific condition (term vs. preterm), general guidelines often suggest:
- Starting GIR: 4 to 6 mg/kg/min is a common starting point for neonates.
- Maintenance: Often titrated up to 6–8 mg/kg/min as tolerated.
- Maximum: Typically capped around 12–14 mg/kg/min, though higher rates may be needed in hyperinsulinism.
Disclaimer: This calculator is a support tool. Always verify calculations and follow your institution's specific clinical protocols.