How to Calculate Estimated Glomerular Filtration Rate

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eGFR Calculator (CKD-EPI 2021)

Male Female
Your Estimated GFR:
mL/min/1.73m²

How to Calculate eGFR

Estimated Glomerular Filtration Rate (eGFR) is a blood test used to check how well your kidneys are working. Since the kidneys filter waste products from the blood, a lower eGFR suggests that kidney function may be impaired.

The standard formula used today is the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) equation. As of 2021, the updated formula removes race as a variable to ensure more equitable care, focusing instead on serum creatinine, age, and sex.

The CKD-EPI (2021) Formula

The calculation follows this mathematical structure:

eGFR = 142 × min(Scr/κ, 1)α × max(Scr/κ, 1)-1.200 × 0.9938Age × [1.012 if female]

  • Scr: Serum Creatinine in mg/dL
  • κ (Kappa): 0.7 for females, 0.9 for males
  • α (Alpha): -0.241 for females, -0.302 for males

Interpreting Your Results

eGFR Level CKD Stage Description
90 or higher Stage 1 Normal kidney function (if other signs of kidney damage exist)
60 to 89 Stage 2 Mildly decreased function
45 to 59 Stage 3a Mild to moderate decrease
30 to 44 Stage 3b Moderate to severe decrease
15 to 29 Stage 4 Severely decreased function
Less than 15 Stage 5 Kidney failure (End-stage renal disease)

Example Calculation

If a 55-year-old male has a serum creatinine of 1.2 mg/dL:

  1. Inputs: Scr = 1.2, Age = 55, Male.
  2. Parameters: κ = 0.9, α = -0.302.
  3. Result: Approximately 74 mL/min/1.73m².
  4. Classification: Stage 2 (Mildly decreased function).

Note: This calculator is for educational purposes. Clinical decisions should always be made in consultation with a medical professional.

function calculateEGFR() { var scr = parseFloat(document.getElementById('scr').value); var age = parseFloat(document.getElementById('age').value); var sex = document.getElementById('gender').value; if (isNaN(scr) || isNaN(age) || scr <= 0 || age = 90) { stage = "Stage 1 (Normal)"; color = "#27ae60"; desc = "Your eGFR is in the normal range. If you have other evidence of kidney damage (like protein in the urine), this is classified as Stage 1 CKD."; } else if (finalResult >= 60) { stage = "Stage 2 (Mild Decrease)"; color = "#f1c40f"; textColor = "#000"; desc = "A result between 60-89 indicates a mild decrease in kidney function."; } else if (finalResult >= 45) { stage = "Stage 3a (Mild-Moderate Decrease)"; color = "#e67e22"; desc = "This indicates a mild to moderate loss of kidney function. Consult a physician for monitoring."; } else if (finalResult >= 30) { stage = "Stage 3b (Moderate-Severe Decrease)"; color = "#d35400"; desc = "This indicates a moderate to severe loss of kidney function. Medical management is typically required."; } else if (finalResult >= 15) { stage = "Stage 4 (Severe Decrease)"; color = "#c0392b"; desc = "This indicates a severe loss of kidney function. You may be approaching kidney failure."; } else { stage = "Stage 5 (Kidney Failure)"; color = "#000000"; desc = "This is end-stage renal disease (ESRD). Urgent medical attention is required."; } var resBox = document.getElementById('resultBox'); var valEl = document.getElementById('egfrValue'); var stageEl = document.getElementById('egfrStage'); var descEl = document.getElementById('stageDesc'); valEl.innerHTML = finalResult; stageEl.innerHTML = stage; stageEl.style.backgroundColor = color; stageEl.style.color = textColor; descEl.innerHTML = desc; resBox.style.display = 'block'; resBox.scrollIntoView({ behavior: 'smooth', block: 'nearest' }); }

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