Privigen Infusion Rate Calculator

Calculate patient-specific dosing and titration rates

0.5 (Initial Rate) 1.0 2.0 4.0 8.0 (Maximum Rate)

Infusion Summary

Total Dose 0 grams

Total Volume (10%) 0 mL

Current Infusion Pump Setting: 0 mL/hour

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Understanding Privigen Infusion Protocols

Privigen is a 10% liquid preparation of Immune Globulin Intravenous (Human) (IGIV). Calculating the correct infusion rate is critical for patient safety and to minimize infusion-related adverse reactions.

Dosing & Administration Guidelines

The standard concentration of Privigen is 100 mg/mL (10%). Infusion rates are typically calculated based on the patient's body weight and the specific indication (PID, ITP, or CIDP).

• Initial Infusion Rate: Usually started at 0.5 mg/kg/min (0.3 mL/kg/hr).
• Maintenance Rate: If well-tolerated, the rate may be gradually increased to a maximum of 8 mg/kg/min (4.8 mL/kg/hr).
• Titration: It is standard clinical practice to increase the rate every 15-30 minutes as tolerated by the patient.

Example Calculation

For a patient weighing 70 kg receiving a dose of 0.4 g/kg at a target maintenance rate of 4 mg/kg/min:

1. Total Dose: 70 kg × 0.4 g/kg = 28 grams.
2. Total Volume: 28 grams / 0.10 (10%) = 280 mL.
3. Rate (mL/hr): (4 mg/kg/min × 70 kg × 60 min) / 100 mg per mL = 168 mL/hr.

Disclaimer: This calculator is for educational purposes for healthcare professionals. Medical decisions should be based on clinical judgment and the full prescribing information provided by CSL Behring. Always verify calculations manually before administration.

function calculateInfusion() { var weight = parseFloat(document.getElementById('weightKg').value); var dosePerKg = parseFloat(document.getElementById('prescribedDose').value); var rateMgPerKgMin = parseFloat(document.getElementById('infusionRateMg').value); if (!weight || weight <= 0 || !dosePerKg || dosePerKg <= 0) { alert("Please enter valid weight and dose values."); return; } // Calculation Logic // Privigen is 10% = 100mg/mL var totalDoseGrams = weight * dosePerKg; var totalVolumeMl = totalDoseGrams * 10; // Since 1g = 10mL in a 10% solution // Formula for mL/hr: (mg/kg/min * weight * 60) / 100 var mlPerHour = (rateMgPerKgMin * weight * 60) / 100; // Update Display document.getElementById('resTotalGrams').innerText = totalDoseGrams.toFixed(1); document.getElementById('resTotalVolume').innerText = totalVolumeMl.toFixed(0); document.getElementById('resPumpRate').innerText = mlPerHour.toFixed(1); // Show Results document.getElementById('resultsArea').style.display = 'block'; }