Privigen Infusion Rate Calculator
Clinical Tool for Immune Globulin Intravenous (10%) Administration
Calculation Results
Infusion Flow Rate:
Total Volume:
Infusion Duration:
Concentration:
100 mg/mL (10%)
Understanding Privigen Rate Calculations
Privigen is a 10% liquid preparation of Immune Globulin Intravenous (Human). Accurate calculation of the infusion rate is critical for patient safety and to minimize adverse infusion-related reactions. The dosage is typically based on the patient's weight in kilograms and the concentration of the product.
The Formula
To convert a prescribed dose in mg/kg/min to a pump setting in mL/hr, the following logic is applied:
- Step 1: Calculate mg per minute: Weight (kg) × Dose Rate (mg/kg/min).
- Step 2: Convert mg to mL: Since Privigen is 100 mg/mL, Divide mg/min by 100.
- Step 3: Convert minutes to hours: Multiply the result by 60.
Simplified Formula: Rate (mL/hr) = [Dose (mg/kg/min) × Weight (kg) × 0.6]
Typical Titration Schedule
Healthcare providers often follow a titration protocol for the first infusion:
| Stage | Rate (mg/kg/min) | Rate (mL/kg/hr) |
|---|---|---|
| Initial (First 30 min) | 0.5 mg/kg/min | 0.3 mL/kg/hr |
| Maintenance (If tolerated) | Up to 8.0 mg/kg/min | Up to 4.8 mL/kg/hr |
Example Calculation
For a patient weighing 80 kg prescribed an initial rate of 0.5 mg/kg/min:
- 80 kg × 0.5 mg/kg/min = 40 mg/min.
- 40 mg/min ÷ 100 mg/mL = 0.4 mL/min.
- 0.4 mL/min × 60 min = 24 mL/hr.