ACC/AHA 10-Year ASCVD Risk Calculator
This calculator estimates your 10-year risk of developing atherosclerotic cardiovascular disease (ASCVD), which includes heart attack, stroke, and cardiovascular death. It is based on the 2013 ACC/AHA Pooled Cohort Equations and is intended for individuals aged 40-79 years without pre-existing ASCVD.
Understanding Your ASCVD Risk
Atherosclerotic cardiovascular disease (ASCVD) is a condition where plaque builds up inside your arteries, leading to hardening and narrowing. This can restrict blood flow to your heart, brain, and other parts of your body, potentially causing heart attacks, strokes, or peripheral artery disease.
The ACC/AHA 10-Year ASCVD Risk Calculator uses several key factors to estimate your risk:
- Age: Risk generally increases with age.
- Sex: Men typically have a higher risk than women at younger ages.
- Race: African Americans have different risk factor profiles and equations are adjusted accordingly.
- Total and HDL Cholesterol: High total cholesterol and low HDL (good) cholesterol are risk factors.
- Systolic Blood Pressure: High blood pressure (hypertension) significantly increases risk.
- Hypertension Treatment: Being on medication for high blood pressure indicates a managed risk factor, but the underlying condition still contributes to risk.
- Diabetes: Diabetes is a major independent risk factor for ASCVD.
- Smoking Status: Current smoking is a powerful risk factor.
The calculator provides a percentage representing your estimated chance of having a heart attack or stroke within the next 10 years. For example, a 10% risk means that out of 100 people with similar risk factors, about 10 would experience an ASCVD event in the next decade.
Important Note: This calculator is a screening tool and should not replace professional medical advice. It is designed for individuals aged 40-79 who do not already have a history of heart attack, stroke, or other ASCVD. If you have concerns about your cardiovascular health, please consult with your doctor or a qualified healthcare provider. They can interpret your risk score in the context of your overall health and recommend appropriate preventive strategies.
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margin-top: 25px;
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display: none; /* Hidden by default */
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background-color: #f8d7da;
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margin-left: 20px;
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.acc-aha-calculator-container ul li {
margin-bottom: 8px;
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function calculateRisk() {
var age = parseFloat(document.getElementById("age").value);
var sex = document.getElementById("sex").value;
var race = document.getElementById("race").value;
var totalCholesterol = parseFloat(document.getElementById("totalCholesterol").value);
var hdlCholesterol = parseFloat(document.getElementById("hdlCholesterol").value);
var systolicBP = parseFloat(document.getElementById("systolicBP").value);
var onHypertensionTreatment = document.getElementById("onHypertensionTreatment").value === "yes";
var diabetic = document.getElementById("diabetic").value === "yes";
var smoker = document.getElementById("smoker").value === "yes";
var resultDiv = document.getElementById("result");
resultDiv.style.display = "none";
resultDiv.classList.remove("error");
// Input validation
if (isNaN(age) || age 79) {
resultDiv.innerHTML = "Please enter a valid age between 40 and 79 years.";
resultDiv.classList.add("error");
resultDiv.style.display = "block";
return;
}
if (isNaN(totalCholesterol) || totalCholesterol <= 0) {
resultDiv.innerHTML = "Please enter a valid Total Cholesterol (mg/dL).";
resultDiv.classList.add("error");
resultDiv.style.display = "block";
return;
}
if (isNaN(hdlCholesterol) || hdlCholesterol <= 0) {
resultDiv.innerHTML = "Please enter a valid HDL Cholesterol (mg/dL).";
resultDiv.classList.add("error");
resultDiv.style.display = "block";
return;
}
if (isNaN(systolicBP) || systolicBP <= 0) {
resultDiv.innerHTML = "Please enter a valid Systolic Blood Pressure (mmHg).";
resultDiv.classList.add("error");
resultDiv.style.display = "block";
return;
}
// Logarithm values
var ln_age = Math.log(age);
var ln_total_chol = Math.log(totalCholesterol);
var ln_hdl_chol = Math.log(hdlCholesterol);
var ln_sbp = Math.log(systolicBP);
var sum_of_products = 0;
var mean_sum_of_products = 0;
var baseline_survival = 0;
// Coefficients and Mean Values (from 2013 ACC/AHA Guideline, Appendix 2, Table 2)
if (sex === "male" && race === "white") {
// White Men
var coeffs = {
ln_age: 12.344,
ln_total_chol: 11.853,
ln_hdl_chol: -2.664,
ln_sbp_untreated: 2.822,
ln_sbp_treated: 2.761,
smoker: 0.523,
diabetes: 0.618
};
var means = {
ln_age: 5.464,
ln_total_chol: 5.312,
ln_hdl_chol: 3.607,
ln_sbp: 5.000, // Single mean for SBP
smoker: 0.284,
diabetes: 0.070
};
baseline_survival = 0.9144;
sum_of_products =
coeffs.ln_age * ln_age +
coeffs.ln_total_chol * ln_total_chol +
coeffs.ln_hdl_chol * ln_hdl_chol +
(onHypertensionTreatment ? coeffs.ln_sbp_treated : coeffs.ln_sbp_untreated) * ln_sbp +
coeffs.smoker * (smoker ? 1 : 0) +
coeffs.diabetes * (diabetic ? 1 : 0);
mean_sum_of_products =
coeffs.ln_age * means.ln_age +
coeffs.ln_total_chol * means.ln_total_chol +
coeffs.ln_hdl_chol * means.ln_hdl_chol +
(onHypertensionTreatment ? coeffs.ln_sbp_treated : coeffs.ln_sbp_untreated) * means.ln_sbp +
coeffs.smoker * means.smoker +
coeffs.diabetes * means.diabetes;
} else if (sex === "female" && race === "white") {
// White Women
var ln_age_sq = Math.pow(ln_age, 2);
var ln_age_smoker = ln_age * (smoker ? 1 : 0);
var coeffs = {
ln_age: -29.799,
ln_age_sq: 4.884,
ln_total_chol: 13.540,
ln_hdl_chol: -1.951,
ln_sbp_untreated: 1.797,
ln_sbp_treated: 1.764,
smoker: 7.837,
ln_age_smoker: -1.795,
diabetes: 0.658
};
var means = {
ln_age: 5.464,
ln_age_sq: 29.907,
ln_total_chol: 5.312,
ln_hdl_chol: 3.607,
ln_sbp: 5.000, // Single mean for SBP
smoker: 0.284,
ln_age_smoker: 1.550,
diabetes: 0.070
};
baseline_survival = 0.9665;
sum_of_products =
coeffs.ln_age * ln_age +
coeffs.ln_age_sq * ln_age_sq +
coeffs.ln_total_chol * ln_total_chol +
coeffs.ln_hdl_chol * ln_hdl_chol +
(onHypertensionTreatment ? coeffs.ln_sbp_treated : coeffs.ln_sbp_untreated) * ln_sbp +
coeffs.smoker * (smoker ? 1 : 0) +
coeffs.ln_age_smoker * ln_age_smoker +
coeffs.diabetes * (diabetic ? 1 : 0);
mean_sum_of_products =
coeffs.ln_age * means.ln_age +
coeffs.ln_age_sq * means.ln_age_sq +
coeffs.ln_total_chol * means.ln_total_chol +
coeffs.ln_hdl_chol * means.ln_hdl_chol +
(onHypertensionTreatment ? coeffs.ln_sbp_treated : coeffs.ln_sbp_untreated) * means.ln_sbp +
coeffs.smoker * means.smoker +
coeffs.ln_age_smoker * means.ln_age_smoker +
coeffs.diabetes * means.diabetes;
} else if (sex === "male" && race === "african_american") {
// African American Men
var coeffs = {
ln_age: 2.469,
ln_total_chol: 0.302,
ln_hdl_chol: -0.706,
ln_sbp_untreated: 0.449,
ln_sbp_treated: 0.439,
smoker: 0.464,
diabetes: 0.581
};
var means = {
ln_age: 5.464,
ln_total_chol: 5.312,
ln_hdl_chol: 3.607,
ln_sbp: 5.000, // Single mean for SBP
smoker: 0.284,
diabetes: 0.070
};
baseline_survival = 0.8954;
sum_of_products =
coeffs.ln_age * ln_age +
coeffs.ln_total_chol * ln_total_chol +
coeffs.ln_hdl_chol * ln_hdl_chol +
(onHypertensionTreatment ? coeffs.ln_sbp_treated : coeffs.ln_sbp_untreated) * ln_sbp +
coeffs.smoker * (smoker ? 1 : 0) +
coeffs.diabetes * (diabetic ? 1 : 0);
mean_sum_of_products =
coeffs.ln_age * means.ln_age +
coeffs.ln_total_chol * means.ln_total_chol +
coeffs.ln_hdl_chol * means.ln_hdl_chol +
(onHypertensionTreatment ? coeffs.ln_sbp_treated : coeffs.ln_sbp_untreated) * means.ln_sbp +
coeffs.smoker * means.smoker +
coeffs.diabetes * means.diabetes;
} else if (sex === "female" && race === "african_american") {
// African American Women
var ln_age_ln_hdl_chol = ln_age * ln_hdl_chol;
var coeffs = {
ln_age: 17.114,
ln_total_chol: 0.940,
ln_hdl_chol: -18.920,
ln_age_ln_hdl_chol: 4.475,
ln_sbp_untreated: 29.291,
ln_sbp_treated: 27.820,
smoker: 0.691,
diabetes: 0.874
};
var means = {
ln_age: 5.464,
ln_total_chol: 5.312,
ln_hdl_chol: 3.607,
ln_age_ln_hdl_chol: 19.670,
ln_sbp: 5.000, // Single mean for SBP
smoker: 0.284,
diabetes: 0.070
};
baseline_survival = 0.9533;
sum_of_products =
coeffs.ln_age * ln_age +
coeffs.ln_total_chol * ln_total_chol +
coeffs.ln_hdl_chol * ln_hdl_chol +
coeffs.ln_age_ln_hdl_chol * ln_age_ln_hdl_chol +
(onHypertensionTreatment ? coeffs.ln_sbp_treated : coeffs.ln_sbp_untreated) * ln_sbp +
coeffs.smoker * (smoker ? 1 : 0) +
coeffs.diabetes * (diabetic ? 1 : 0);
mean_sum_of_products =
coeffs.ln_age * means.ln_age +
coeffs.ln_total_chol * means.ln_total_chol +
coeffs.ln_hdl_chol * means.ln_hdl_chol +
coeffs.ln_age_ln_hdl_chol * means.ln_age_ln_hdl_chol +
(onHypertensionTreatment ? coeffs.ln_sbp_treated : coeffs.ln_sbp_untreated) * means.ln_sbp +
coeffs.smoker * means.smoker +
coeffs.diabetes * means.diabetes;
} else {
resultDiv.innerHTML = "An unexpected error occurred. Please check your selections.";
resultDiv.classList.add("error");
resultDiv.style.display = "block";
return;
}
var risk_exponent = sum_of_products – mean_sum_of_products;
var ten_year_risk = (1 – Math.pow(baseline_survival, Math.exp(risk_exponent))) * 100;
if (ten_year_risk 100) ten_year_risk = 100; // Risk cannot exceed 100%
resultDiv.innerHTML = "Your estimated 10-Year ASCVD Risk:
" + ten_year_risk.toFixed(1) + "%";
resultDiv.style.display = "block";
}