Blood Gas Calculator

Blood Gas Calculator

Results will appear here.

function calculateBloodGas() { var pH = parseFloat(document.getElementById("phValue").value); var pco2 = parseFloat(document.getElementById("paco2Value").value); var hco3 = parseFloat(document.getElementById("hco3Value").value); var pao2 = parseFloat(document.getElementById("pao2Value").value); if (isNaN(pH) || isNaN(pco2) || isNaN(hco3) || isNaN(pao2) || pH <= 0 || pco2 <= 0 || hco3 <= 0 || pao2 <= 0) { document.getElementById("bloodGasResult").innerHTML = "Please enter valid numerical values for all parameters."; return; } var acidBaseStatus = ""; var primaryProblem = ""; var compensationStatus = ""; // Normal Ranges var normal_pH_min = 7.35; var normal_pH_max = 7.45; var normal_pco2_min = 35; var normal_pco2_max = 45; var normal_hco3_min = 22; var normal_hco3_max = 26; var normal_pao2_min = 80; var normal_pao2_max = 100; // 1. Evaluate pH var pH_status = "Normal"; if (pH normal_pH_max) { acidBaseStatus = "Alkalemia"; pH_status = "Alkalemic"; } else { acidBaseStatus = "Normal pH"; } // 2. Evaluate PaCO2 (Respiratory Component) var respStatus = "Normal Respiratory"; var pco2_status = "Normal"; if (pco2 normal_pco2_max) { respStatus = "Acidosis (Respiratory)"; pco2_status = "High"; } // 3. Evaluate HCO3 (Metabolic Component) var metStatus = "Normal Metabolic"; var hco3_status = "Normal"; if (hco3 normal_hco3_max) { metStatus = "Alkalosis (Metabolic)"; hco3_status = "High"; } // Determine Primary Disorder and Compensation if (acidBaseStatus === "Acidemia") { if (respStatus === "Acidosis (Respiratory)") { primaryProblem = "Respiratory Acidosis"; if (metStatus === "Alkalosis (Metabolic)") { // HCO3 is high, compensating compensationStatus = "Partially Compensated"; } else if (metStatus === "Acidosis (Metabolic)") { // HCO3 is low, mixed primaryProblem = "Mixed Respiratory and Metabolic Acidosis"; } } else if (metStatus === "Acidosis (Metabolic)") { primaryProblem = "Metabolic Acidosis"; if (respStatus === "Alkalosis (Respiratory)") { // PaCO2 is low, compensating compensationStatus = "Partially Compensated"; } else if (respStatus === "Acidosis (Respiratory)") { // PaCO2 is high, mixed primaryProblem = "Mixed Metabolic and Respiratory Acidosis"; } } else { primaryProblem = "Unclear Acidosis"; // Should not happen if pH is truly low and no other primary cause } } else if (acidBaseStatus === "Alkalemia") { if (respStatus === "Alkalosis (Respiratory)") { primaryProblem = "Respiratory Alkalosis"; if (metStatus === "Acidosis (Metabolic)") { // HCO3 is low, compensating compensationStatus = "Partially Compensated"; } else if (metStatus === "Alkalosis (Metabolic)") { // HCO3 is high, mixed primaryProblem = "Mixed Respiratory and Metabolic Alkalosis"; } } else if (metStatus === "Alkalosis (Metabolic)") { primaryProblem = "Metabolic Alkalosis"; if (respStatus === "Acidosis (Respiratory)") { // PaCO2 is high, compensating compensationStatus = "Partially Compensated"; } else if (respStatus === "Alkalosis (Respiratory)") { // PaCO2 is low, mixed primaryProblem = "Mixed Metabolic and Respiratory Alkalosis"; } } else { primaryProblem = "Unclear Alkalosis"; // Should not happen if pH is truly high } } else { // Normal pH (7.35-7.45) if (respStatus === "Acidosis (Respiratory)" && metStatus === "Alkalosis (Metabolic)") { primaryProblem = "Respiratory Acidosis"; compensationStatus = "Fully Compensated"; } else if (respStatus === "Alkalosis (Respiratory)" && metStatus === "Acidosis (Metabolic)") { primaryProblem = "Respiratory Alkalosis"; compensationStatus = "Fully Compensated"; } else if (respStatus === "Normal Respiratory" && metStatus === "Normal Metabolic") { primaryProblem = "Normal Acid-Base Balance"; } else if (respStatus !== "Normal Respiratory" && metStatus !== "Normal Metabolic") { // This covers cases like Mixed Respiratory Acidosis and Metabolic Alkalosis, or vice versa, with normal pH primaryProblem = "Mixed Disorder (with normal pH)"; } else if (respStatus !== "Normal Respiratory") { primaryProblem = "Uncompensated Respiratory Disorder (with normal pH)"; // Acute respiratory disorder } else if (metStatus !== "Normal Metabolic") { primaryProblem = "Uncompensated Metabolic Disorder (with normal pH)"; // Acute metabolic disorder } else { primaryProblem = "Normal Acid-Base Balance"; } } var finalAcidBaseResult = primaryProblem; if (compensationStatus !== "") { finalAcidBaseResult += ", " + compensationStatus; } // Oxygenation Status var oxygenationStatus = ""; var pao2_status = "Normal"; if (pao2 normal_pao2_max) { oxygenationStatus = "Hyperoxemia"; pao2_status = "High"; } else { oxygenationStatus = "Normal Oxygenation"; } // Display results var resultHtml = "

Acid-Base Interpretation:

" + finalAcidBaseResult + ""; resultHtml += "

Oxygenation Status:

" + oxygenationStatus + ""; resultHtml += "

Individual Parameter Status:

    "; resultHtml += "
  • pH: " + pH.toFixed(2) + " (" + pH_status + ")
  • "; resultHtml += "
  • PaCO2: " + pco2.toFixed(1) + " mmHg (" + pco2_status + ")
  • "; resultHtml += "
  • HCO3: " + hco3.toFixed(1) + " mEq/L (" + hco3_status + ")
  • "; resultHtml += "
  • PaO2: " + pao2.toFixed(1) + " mmHg (" + pao2_status + ")
  • "; resultHtml += "
"; document.getElementById("bloodGasResult").innerHTML = resultHtml; }

Understanding Your Blood Gas Results

A blood gas analysis, most commonly an Arterial Blood Gas (ABG), is a crucial diagnostic tool used in medicine to assess a patient's respiratory and metabolic status. It provides vital information about the body's acid-base balance, oxygenation, and ventilation efficiency. This calculator helps you understand the basic interpretation of key ABG parameters.

Key Parameters in a Blood Gas Analysis:

  • pH: This measures the acidity or alkalinity of the blood. A normal pH range is typically 7.35 to 7.45.
    • pH < 7.35 indicates Acidemia (too much acid).
    • pH > 7.45 indicates Alkalemia (too much base).
  • PaCO2 (Partial pressure of carbon dioxide): This reflects the respiratory component of acid-base balance. CO2 is an acid, and its levels are primarily regulated by the lungs. A normal range is usually 35-45 mmHg.
    • PaCO2 < 35 mmHg suggests hyperventilation (blowing off too much CO2), leading to respiratory alkalosis.
    • PaCO2 > 45 mmHg suggests hypoventilation (retaining too much CO2), leading to respiratory acidosis.
  • HCO3 (Bicarbonate): This represents the metabolic (renal) component of acid-base balance. Bicarbonate is a base, and its levels are primarily regulated by the kidneys. A normal range is typically 22-26 mEq/L.
    • HCO3 < 22 mEq/L suggests metabolic acidosis (loss of base or gain of acid).
    • HCO3 > 26 mEq/L suggests metabolic alkalosis (gain of base or loss of acid).
  • PaO2 (Partial pressure of oxygen): This measures the amount of oxygen dissolved in the arterial blood, indicating the efficiency of oxygen transfer from the lungs to the blood. A normal range for adults on room air is typically 80-100 mmHg.
    • PaO2 < 80 mmHg indicates Hypoxemia (low blood oxygen).
    • PaO2 > 100 mmHg indicates Hyperoxemia (high blood oxygen), often seen with supplemental oxygen.

Interpreting Acid-Base Balance:

The interpretation of ABG results involves a systematic approach to identify the primary disorder and any compensatory mechanisms. The body tries to maintain a normal pH by compensating for imbalances. For example, if there's a respiratory problem, the kidneys will try to compensate metabolically, and vice-versa.

Common Acid-Base Disorders:

  • Respiratory Acidosis: Low pH, High PaCO2. Caused by hypoventilation (e.g., COPD, opioid overdose).
  • Respiratory Alkalosis: High pH, Low PaCO2. Caused by hyperventilation (e.g., anxiety, pain, hypoxia).
  • Metabolic Acidosis: Low pH, Low HCO3. Caused by excess acid production or bicarbonate loss (e.g., diabetic ketoacidosis, kidney failure, severe diarrhea).
  • Metabolic Alkalosis: High pH, High HCO3. Caused by excess bicarbonate or acid loss (e.g., severe vomiting, diuretic use).

Compensation:

When a primary acid-base disorder occurs, the body attempts to normalize the pH by adjusting the opposing system. This is called compensation.

  • Partial Compensation: The pH is still abnormal, but the compensatory mechanism (PaCO2 or HCO3) is moving in the opposite direction to try and correct it.
  • Full Compensation: The pH has returned to the normal range (7.35-7.45), but both the primary and compensatory parameters remain abnormal.
  • Uncompensated: The pH is abnormal, and the compensatory mechanism has not yet begun or is not effective.

Examples of Blood Gas Interpretation:

Let's use the calculator with some realistic scenarios:

Example 1: Normal Blood Gas

  • pH: 7.40
  • PaCO2: 40 mmHg
  • HCO3: 24 mEq/L
  • PaO2: 90 mmHg
  • Calculator Result: Normal Acid-Base Balance, Normal Oxygenation.

Example 2: Uncompensated Respiratory Acidosis

  • pH: 7.25 (Acidemic)
  • PaCO2: 60 mmHg (High)
  • HCO3: 25 mEq/L (Normal)
  • PaO2: 70 mmHg (Hypoxemic)
  • Calculator Result: Respiratory Acidosis, Hypoxemia.
  • Interpretation: The low pH and high PaCO2 indicate respiratory acidosis. The normal HCO3 suggests no metabolic compensation has occurred yet, or it's an acute event.

Example 3: Partially Compensated Metabolic Acidosis

  • pH: 7.30 (Acidemic)
  • PaCO2: 30 mmHg (Low)
  • HCO3: 15 mEq/L (Low)
  • PaO2: 95 mmHg (Normal)
  • Calculator Result: Metabolic Acidosis, Partially Compensated, Normal Oxygenation.
  • Interpretation: The low pH and low HCO3 indicate metabolic acidosis. The low PaCO2 shows the respiratory system is trying to compensate by blowing off CO2, but the pH is still acidic, so it's partially compensated.

Example 4: Fully Compensated Respiratory Alkalosis

  • pH: 7.42 (Normal, but on the alkalotic side)
  • PaCO2: 28 mmHg (Low)
  • HCO3: 18 mEq/L (Low)
  • PaO2: 92 mmHg (Normal)
  • Calculator Result: Respiratory Alkalosis, Fully Compensated, Normal Oxygenation.
  • Interpretation: The pH is normal, but both PaCO2 and HCO3 are abnormal. The low PaCO2 indicates a primary respiratory alkalosis, and the low HCO3 shows metabolic compensation has brought the pH back to normal.

Important Considerations:

This calculator provides a basic interpretation of common blood gas parameters. It is not a substitute for professional medical advice or comprehensive clinical assessment. Advanced ABG interpretation often involves additional parameters like Base Excess (BE), Anion Gap, and Delta-Delta calculations, which provide further insights into complex mixed acid-base disorders. Always consult with a healthcare professional for diagnosis and treatment.

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