Calculated LDL Cholesterol Calculator
Estimate your Low-Density Lipoprotein (LDL) using the Friedewald Equation
Understanding Calculated LDL Cholesterol
Low-density lipoprotein (LDL) is often referred to as "bad" cholesterol. High levels of LDL lead to a buildup of cholesterol in your arteries, increasing the risk of cardiovascular disease. While direct tests exist, most laboratories use the Friedewald Equation to estimate LDL levels from a standard lipid panel.
The Friedewald Formula
The standard formula used in this calculator is:
LDL Level Categories (mg/dL)
- Optimal: Less than 100 mg/dL
- Near Optimal: 100 – 129 mg/dL
- Borderline High: 130 – 159 mg/dL
- High: 160 – 189 mg/dL
- Very High: 190 mg/dL or higher
Real-Life Calculation Example
Suppose a patient receives the following lipid panel results:
- Total Cholesterol: 210 mg/dL
- HDL Cholesterol: 55 mg/dL
- Triglycerides: 140 mg/dL
Step 1: Calculate VLDL (Triglycerides / 5) = 140 / 5 = 28.
Step 2: Subtract HDL and VLDL from Total Cholesterol = 210 – 55 – 28 = 127 mg/dL.
This result (127 mg/dL) falls into the Near Optimal category.
When is this calculation NOT accurate?
The Friedewald equation has limitations. It should not be used if:
- Triglycerides are over 400 mg/dL: At these levels, the formula significantly underestimates LDL.
- The patient is not fasting: Triglyceride levels fluctuate significantly after meals, leading to inaccurate LDL estimates.
- Type III Hyperlipoproteinemia: A rare genetic condition that alters the composition of lipoproteins.