Homeostatic Model Assessment for Insulin Resistance
mg/dL
mmol/L
Your HOMA-IR Score:
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What is HOMA-IR?
HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a mathematical calculation used by clinical researchers and healthcare professionals to assess how hard the body has to work to control blood sugar levels. It estimates insulin sensitivity and the functional capacity of pancreatic beta-cells.
The HOMA-IR Formula
The calculation differs slightly based on the units used for blood glucose:
Using mg/dL: (Insulin × Glucose) / 405
Using mmol/L: (Insulin × Glucose) / 22.5
Understanding Your HOMA-IR Results
While lab-specific ranges may vary, general clinical guidelines suggest:
HOMA-IR Value
Interpretation
Less than 1.0
Optimal Insulin Sensitivity
1.0 to 1.9
Early Insulin Resistance
Greater than 2.9
Significant Insulin Resistance
Why Track Insulin Resistance?
High HOMA-IR scores are often early warning signs for metabolic syndrome, Type 2 diabetes, and cardiovascular health issues. Often, insulin levels rise long before blood sugar levels (glucose) become clinically abnormal. Detecting this early allows for lifestyle interventions through diet and exercise to reverse the trend.
Disclaimer: This calculator is for educational purposes only and should not replace professional medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment plans.
function calculateHomaIR() {
var insulin = parseFloat(document.getElementById('fastingInsulin').value);
var glucose = parseFloat(document.getElementById('fastingGlucose').value);
var unit = document.getElementById('glucoseUnit').value;
var resultWrapper = document.getElementById('homaResultWrapper');
var scoreDisplay = document.getElementById('homaScore');
var categoryDisplay = document.getElementById('homaCategory');
var interpretationDisplay = document.getElementById('homaInterpretation');
if (isNaN(insulin) || isNaN(glucose) || insulin <= 0 || glucose <= 0) {
alert("Please enter valid positive numbers for both Insulin and Glucose.");
return;
}
var homaIR = 0;
if (unit === 'mgdl') {
homaIR = (insulin * glucose) / 405;
} else {
homaIR = (insulin * glucose) / 22.5;
}
var score = homaIR.toFixed(2);
scoreDisplay.innerText = score;
resultWrapper.style.display = 'block';
var category = "";
var bgColor = "";
var textColor = "#fff";
var description = "";
if (homaIR = 1.0 && homaIR 1.9 && homaIR <= 2.9) {
category = "Moderate Resistance";
bgColor = "#e67e22";
description = "Your levels indicate moderate insulin resistance, common in metabolic syndrome.";
} else {
category = "High Resistance";
bgColor = "#c0392b";
description = "High levels suggest significant insulin resistance. Consult a healthcare provider.";
}
categoryDisplay.innerText = category;
categoryDisplay.style.backgroundColor = bgColor;
categoryDisplay.style.color = textColor;
interpretationDisplay.innerText = description;
resultWrapper.scrollIntoView({ behavior: 'smooth', block: 'nearest' });
}