ESR (Erythrocyte Sedimentation Rate) Calculator
Calculate Westergren ESR and Reference Range Estimates
How to Calculate Erythrocyte Sedimentation Rate
The Erythrocyte Sedimentation Rate (ESR) is a common hematology test used to detect non-specific inflammation in the body. It measures how quickly red blood cells (erythrocytes) sink to the bottom of a vertical tube of anticoagulated blood.
The Basic ESR Formula
In a clinical setting using the Westergren method, the formula is straightforward:
Calculating Expected Normal Ranges (Miller Formula)
Because ESR naturally increases with age, clinicians often use the Miller Formula to estimate the upper limit of normal for a specific patient:
- For Men: Age (years) / 2
- For Women: (Age (years) + 10) / 2
Example Calculation
If a 60-year-old female has a blood sample where the plasma-erythrocyte interface drops 30mm in 1 hour:
- Measured ESR: 30 mm / 1 hr = 30 mm/hr.
- Normal Limit: (60 + 10) / 2 = 35 mm/hr.
- Interpretation: Since 30 is less than 35, this result is within the age-adjusted normal range.
Factors Affecting Results
ESR can be elevated by factors other than inflammation, including anemia, pregnancy, and kidney disease. Conversely, conditions like polycythemia or sickle cell anemia can cause abnormally low ESR readings. Always consult a healthcare professional for clinical diagnosis.