Lidocaine Infusion Rate Calculation Formula

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Lidocaine Infusion Rate Calculator

Commonly 2000mg (2g)
Commonly 500mL or 250mL

Calculated Infusion Parameters:

Concentration: 0 mg/mL

Infusion Rate: 0 mL/hr

Understanding the Lidocaine Infusion Rate Calculation Formula

Lidocaine is a Class 1b anti-arrhythmic drug often administered via continuous intravenous infusion to treat ventricular arrhythmias. Because medical infusion pumps are typically programmed in milliliters per hour (mL/hr), but orders are written in milligrams per minute (mg/min), clinicians must perform a conversion calculation.

The Core Formula

To determine the pump rate, you first need to establish the concentration of the solution and then convert the time unit from minutes to hours.

Step 1: Concentration (mg/mL) = Total mg / Total mL
Step 2: Rate (mL/hr) = [Dose (mg/min) × 60 min] / Concentration (mg/mL)

Standard Concentrations

Lidocaine is frequently supplied in premixed bags. The most common concentrations are:

  • 4 mg/mL: (2 grams in 500 mL or 1 gram in 250 mL)
  • 8 mg/mL: (2 grams in 250 mL)

Practical Example

If a physician orders a Lidocaine infusion at 2 mg/min using a 500 mL bag containing 2 grams (2000 mg) of Lidocaine:

  1. Concentration: 2000 mg / 500 mL = 4 mg/mL.
  2. Hourly Dose: 2 mg/min × 60 min = 120 mg/hr.
  3. Pump Rate: 120 mg/hr / 4 mg/mL = 30 mL/hr.

Clinical Precautions

Lidocaine toxicity is a serious risk. Monitor patients for signs of Central Nervous System (CNS) toxicity, such as tremors, slurred speech, or seizures. Always double-check calculations and pump settings, as infusion errors can lead to cardiac arrest or neurological distress. This calculator is for educational purposes and should be verified against hospital protocols.

function calculateLidoRate() { var dose = parseFloat(document.getElementById("desiredDose").value); var totalMg = parseFloat(document.getElementById("totalLido").value); var totalMl = parseFloat(document.getElementById("totalVolume").value); var resultDiv = document.getElementById("lidoResult"); if (isNaN(dose) || isNaN(totalMg) || isNaN(totalMl) || dose <= 0 || totalMg <= 0 || totalMl <= 0) { alert("Please enter valid positive numbers for all fields."); resultDiv.style.display = "none"; return; } // Step 1: Calculate concentration (mg/mL) var concentration = totalMg / totalMl; // Step 2: Convert mg/min to mg/hr var mgPerHour = dose * 60; // Step 3: Calculate mL per hour var mlPerHour = mgPerHour / concentration; // Display Results document.getElementById("resConcentration").innerText = concentration.toFixed(2); document.getElementById("resRate").innerText = mlPerHour.toFixed(1); resultDiv.style.display = "block"; }

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