This calculator provides an estimated risk of developing prostate cancer based on several key factors.
Please consult with a healthcare professional for personalized advice.
6 (Grade Group 1)
7 (3+4) (Grade Group 2)
7 (4+3) (Grade Group 3)
8 (Grade Group 4)
9-10 (Grade Group 5)
No
Yes (One first-degree relative)
Yes (Two or more first-degree relatives, or one diagnosed at < 60 years old)
White
Black or African American
Hispanic
Asian
Other
Your Estimated Prostate Cancer Risk
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This is an estimate. Consult your doctor for accurate diagnosis and treatment.
Understanding Prostate Cancer Risk Factors
Prostate cancer is a significant health concern for men worldwide. While not all prostate cancers require treatment, understanding your personal risk factors is crucial for proactive health management and early detection. This calculator aims to provide an estimated risk score based on commonly accepted factors, but it is not a substitute for professional medical advice.
Key Factors Influencing Risk:
Age: The risk of prostate cancer increases significantly with age. Most cases are diagnosed in men over 65.
PSA Level (Prostate-Specific Antigen): PSA is a protein produced by cells of the prostate gland. Elevated PSA levels in the blood can indicate the presence of prostate cancer, but also other non-cancerous conditions like prostatitis or benign prostatic hyperplasia (BPH). A higher PSA level generally correlates with a higher risk.
Gleason Score / Grade Group: This score, determined by a pathologist examining a biopsy sample, describes how aggressive the cancer cells look. A higher Gleason score (or Grade Group) indicates a more aggressive cancer and thus a higher risk of progression and recurrence.
Family History: Having a close relative (father, brother, son) diagnosed with prostate cancer increases your risk. The risk is even higher if multiple relatives are affected or if they were diagnosed at a younger age (under 60).
Race/Ethnicity: Certain racial and ethnic groups have different rates of prostate cancer. For example, Black men have a higher incidence and mortality rate from prostate cancer compared to White men. The reasons are complex and likely involve a combination of genetic, environmental, and socioeconomic factors.
How the Calculator Works (Simplified Model):
This calculator uses a simplified scoring system inspired by clinical risk stratification tools. Each input is assigned a weighted score. These scores are summed up, and the total score is then mapped to a general risk category.
Scoring Breakdown (Illustrative, not exact clinical formula):
Age: Older age adds to the risk score.
PSA Level: Higher PSA values contribute exponentially to the risk score.
Gleason Score/Grade Group: Higher scores (e.g., 9-10) contribute significantly more than lower scores (e.g., 6).
Family History: Multiple affected relatives or early diagnosis adds more points than a single relative diagnosed later in life.
Race/Ethnicity: Certain groups associated with higher risk receive a slight adjustment to their score.
The final score is then categorized into general risk levels such as "Low Risk," "Moderate Risk," or "High Risk."
Importance of Early Detection and Consultation:
Regular screening, including PSA tests and digital rectal exams (DRE), can help detect prostate cancer early, often when it is most treatable. Discuss screening guidelines and your individual risk with your doctor, especially if you have multiple risk factors. Early detection can significantly improve treatment outcomes and long-term prognosis.
function calculateRisk() {
var age = parseFloat(document.getElementById("age").value);
var psaLevel = parseFloat(document.getElementById("psaLevel").value);
var gleasonScore = document.getElementById("gleasonScore").value;
var familyHistory = parseInt(document.getElementById("familyHistory").value);
var race = document.getElementById("race").value;
var resultDiv = document.getElementById("result");
var resultValueSpan = document.getElementById("result-value");
var riskLevelP = document.getElementById("risk-level");
// — Input Validation —
if (isNaN(age) || age <= 0 ||
isNaN(psaLevel) || psaLevel < 0 ||
!gleasonScore ||
isNaN(familyHistory) || familyHistory 60) riskScore += (age – 60) * 0.1;
if (age > 70) riskScore += (age – 70) * 0.1; // Additional increase
// PSA Level factor (exponential scaling for higher PSAs)
if (psaLevel > 4) riskScore += (psaLevel – 4) * 1.5;
if (psaLevel > 10) riskScore += (psaLevel – 10) * 2.0; // Higher impact
if (psaLevel > 20) riskScore += (psaLevel – 20) * 3.0;
// Gleason Score/Grade Group factor
if (gleasonScore === "6") riskScore += 2;
else if (gleasonScore === "7a") riskScore += 5;
else if (gleasonScore === "7b") riskScore += 7;
else if (gleasonScore === "8") riskScore += 10;
else if (gleasonScore === "9") riskScore += 15;
// Family History factor
riskScore += familyHistory * 3; // Base points for history
// Race/Ethnicity factor (simplified adjustment)
if (race === "black") riskScore += 2; // Slightly higher base risk
if (race === "hispanic") riskScore += 0.5; // Minor adjustment
// — Risk Level Determination —
var riskLevel = "";
var riskPercentage = 0;
// This mapping is illustrative and not based on a specific clinical calculator's exact formula.
// Clinical calculators often use complex regression models.
if (riskScore < 5) {
riskPercentage = Math.min(15, riskScore * 2.5); // Max 15% for low scores
riskLevel = "Low Risk";
} else if (riskScore < 15) {
riskPercentage = 15 + (riskScore – 5) * 2.0; // Gradual increase
riskLevel = "Moderate Risk";
} else if (riskScore < 30) {
riskPercentage = 35 + (riskScore – 15) * 1.5; // Steeper increase
riskLevel = "Elevated Risk";
} else {
riskPercentage = 50 + (riskScore – 30) * 1.0; // High risk
riskLevel = "High Risk";
}
// Cap the percentage at a reasonable upper limit (e.g., 95%)
riskPercentage = Math.min(riskPercentage, 95);
riskPercentage = Math.max(riskPercentage, 5); // Ensure a minimum displayed value
// — Display Results —
resultValueSpan.textContent = riskPercentage.toFixed(1) + "%";
riskLevelP.textContent = "Estimated Risk Level: " + riskLevel;
resultDiv.style.display = "block";
}