Determining the total intake of Isotretinoin is crucial for treatment success and minimizing relapse. Use this Accutane Cumulative Dose Calculator to track your progress or plan your treatment course based on clinical guidelines.
Accutane Cumulative Dose Calculator
Leave one field blank to calculate its value.
Accutane Cumulative Dose Formula
Source: American Academy of Dermatology (AAD), Mayo Clinic
Variables:
- Body Weight: The patient’s current weight in kilograms (kg).
- Daily Dosage: The amount of Isotretinoin taken each day in milligrams (mg).
- Duration: The total length of the treatment course in days.
- Cumulative Dose: The total target dose per kilogram, usually 120-150 mg/kg.
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What is Accutane Cumulative Dose?
The cumulative dose refers to the total amount of isotretinoin (Accutane) a patient ingests over their entire course of treatment. Clinical research suggests that reaching a specific threshold—typically between 120 mg/kg and 150 mg/kg—significantly reduces the risk of acne relapse.
While daily dosages may vary based on a patient’s tolerance and side effects, the focus for dermatologists is often ensuring the final “total” meets these evidence-based targets for long-term clearance.
How to Calculate Accutane Cumulative Dose (Example)
- Identify the patient’s weight (e.g., 60kg).
- Determine the daily dose (e.g., 40mg/day).
- Track the duration (e.g., 6 months or 180 days).
- Multiply daily dose by days: 40 × 180 = 7,200 mg total.
- Divide total mg by weight: 7,200 / 60 = 120 mg/kg.
Frequently Asked Questions (FAQ)
What is the ideal cumulative dose? Most dermatologists aim for 120-150 mg/kg, though some studies suggest up to 220 mg/kg for severe cases.
What happens if I don’t reach the target? Failing to reach the cumulative target is associated with a higher rate of acne returning after treatment ends.
Can I take a lower dose for longer? Yes, “low-dose” long-term therapy is a common strategy to minimize side effects while still reaching the target cumulative dose.
Should I calculate based on “ideal” or “actual” weight? Most protocols use actual body weight, but consult your dermatologist if significant weight changes occur.