Tesamorelin Dosage Calculator
This calculator helps determine the correct concentration and injection volume for Tesamorelin (Egrifta SV) based on the prescribed dose and reconstitution instructions. Always follow your healthcare provider's specific instructions and the product's prescribing information.
Understanding Tesamorelin Dosage
Tesamorelin, marketed as Egrifta SV, is a synthetic growth hormone-releasing factor (GRF) analogue used to reduce excess abdominal fat in HIV-infected patients with lipodystrophy. Accurate dosing and reconstitution are crucial for its safe and effective use.
How Tesamorelin is Supplied and Reconstituted
Tesamorelin is typically supplied as a lyophilized powder in a single-dose vial. It requires reconstitution with sterile water for injection before administration. The standard product usually contains 2 mg of Tesamorelin per vial, and it is commonly reconstituted with 0.8 mL of sterile water. This process creates a solution with a specific concentration that allows for the accurate measurement of the prescribed dose.
The Importance of Accurate Calculation
The prescribed dose of Tesamorelin is usually 2 mg once daily. However, understanding the concentration after reconstitution is vital to ensure the correct volume is drawn into the syringe for injection. If the reconstitution volume or the amount of Tesamorelin per vial varies (e.g., due to different product formulations or specific medical instructions), the resulting concentration and required injection volume will change.
Using the Calculator
- Prescribed Tesamorelin Dose (mg): Enter the daily dose of Tesamorelin your healthcare provider has prescribed. The standard dose is 2 mg.
- Tesamorelin per Vial (mg): Input the total amount of Tesamorelin contained in one vial, as indicated on the product label. This is typically 2 mg.
- Reconstitution Volume (mL): Enter the exact volume of sterile water for injection used to reconstitute the Tesamorelin powder, as per the product's instructions. This is commonly 0.8 mL.
The calculator will then provide:
- Concentration after Reconstitution (mg/mL): This tells you how many milligrams of Tesamorelin are present in each milliliter of the reconstituted solution.
- Volume to Inject (mL): This is the precise volume of the reconstituted solution you need to draw into your syringe to administer the prescribed dose.
Example Calculation:
Let's say the prescribed dose is 2 mg, the vial contains 2 mg of Tesamorelin, and you reconstitute it with 0.8 mL of sterile water.
- Concentration: 2 mg / 0.8 mL = 2.5 mg/mL
- Volume to Inject: 2 mg (prescribed dose) / 2.5 mg/mL (concentration) = 0.8 mL
This means for a 2 mg dose, you would inject 0.8 mL of the reconstituted solution.
Disclaimer: This calculator is for informational and educational purposes only and should not replace professional medical advice. Always consult with your doctor or pharmacist regarding your specific Tesamorelin dosage and administration instructions. Incorrect dosing can lead to adverse health effects.