.vaso-calc-header {
text-align: center;
margin-bottom: 30px;
}
.vaso-calc-header h2 {
color: #2c5282;
margin-bottom: 10px;
}
.vaso-input-group {
background: #ffffff;
padding: 20px;
border-radius: 8px;
box-shadow: 0 2px 4px rgba(0,0,0,0.05);
margin-bottom: 20px;
border-left: 5px solid #3182ce;
}
.vaso-grid {
display: grid;
grid-template-columns: 1fr 1fr;
gap: 20px;
}
@media (max-width: 600px) {
.vaso-grid {
grid-template-columns: 1fr;
}
}
.vaso-field {
margin-bottom: 15px;
}
.vaso-field label {
display: block;
font-weight: 600;
color: #4a5568;
margin-bottom: 5px;
font-size: 0.95rem;
}
.vaso-field input {
width: 100%;
padding: 10px;
border: 1px solid #cbd5e0;
border-radius: 4px;
font-size: 1rem;
box-sizing: border-box;
}
.vaso-field input:focus {
outline: none;
border-color: #3182ce;
box-shadow: 0 0 0 3px rgba(49, 130, 206, 0.1);
}
.vaso-help {
font-size: 0.8rem;
color: #718096;
margin-top: 4px;
}
.vaso-btn {
width: 100%;
background: #2b6cb0;
color: white;
border: none;
padding: 15px;
font-size: 1.1rem;
font-weight: bold;
border-radius: 6px;
cursor: pointer;
transition: background 0.2s;
margin-top: 10px;
}
.vaso-btn:hover {
background: #2c5282;
}
.vaso-result {
margin-top: 25px;
background: #ebf8ff;
border: 1px solid #bee3f8;
border-radius: 6px;
padding: 20px;
display: none;
}
.vaso-result h3 {
margin-top: 0;
color: #2a4365;
font-size: 1.2rem;
border-bottom: 1px solid #bee3f8;
padding-bottom: 10px;
}
.vaso-res-row {
display: flex;
justify-content: space-between;
margin-bottom: 10px;
align-items: center;
}
.vaso-res-label {
color: #4a5568;
font-weight: 500;
}
.vaso-res-value {
font-weight: bold;
font-size: 1.2rem;
color: #2b6cb0;
}
.vaso-content {
margin-top: 40px;
line-height: 1.6;
color: #2d3748;
}
.vaso-content h3 {
color: #2c5282;
margin-top: 25px;
}
.vaso-content ul {
padding-left: 20px;
}
.vaso-content li {
margin-bottom: 10px;
}
.vaso-disclaimer {
background: #fff5f5;
border-left: 4px solid #fc8181;
padding: 15px;
margin-top: 30px;
font-size: 0.9rem;
color: #c53030;
}
function calculateVasoRate() {
// Get input values
var drugUnits = document.getElementById('drugUnits').value;
var totalVolume = document.getElementById('totalVolume').value;
var desiredDose = document.getElementById('desiredDose').value;
var resultBox = document.getElementById('vasoResult');
// Validation
if (drugUnits === "" || totalVolume === "" || desiredDose === "") {
alert("Please fill in all fields (Total Units, Total Volume, and Desired Dose).");
return;
}
var unitsVal = parseFloat(drugUnits);
var volumeVal = parseFloat(totalVolume);
var doseVal = parseFloat(desiredDose);
if (isNaN(unitsVal) || isNaN(volumeVal) || isNaN(doseVal) || volumeVal <= 0 || unitsVal <= 0) {
alert("Please enter valid positive numbers.");
return;
}
// Calculation Logic
// 1. Calculate Concentration (Units/mL)
var concentration = unitsVal / volumeVal;
// 2. Calculate Flow Rate (mL/hr)
// Formula: (Dose [units/min] * 60 [min/hr]) / Concentration [units/mL]
var flowRate = (doseVal * 60) / concentration;
// 3. Calculate Approx Duration (hours)
var duration = volumeVal / flowRate;
// Display Results
document.getElementById('resConcentration').innerHTML = concentration.toFixed(4) + " Units/mL";
document.getElementById('resFlowRate').innerHTML = flowRate.toFixed(2) + " mL/hr";
document.getElementById('resDuration').innerHTML = duration.toFixed(1) + " Hours";
// Show result div
resultBox.style.display = "block";
}
Vasopressin Infusion Rate Calculator
Calculate the IV pump flow rate (mL/hr) based on desired units/min dose.
Total units in the IV bag (e.g., 20 Units, 40 Units).
Total volume of the solution (e.g., 100 mL).
Target dose per minute (Standard septic shock dose: 0.03 units/min).
Calculation Results
Concentration:
–
IV Pump Rate:
–
Infusion Duration (Approx):
–
How to Calculate Vasopressin Drip Rates
Vasopressin (arginine vasopressin) is a potent vasoconstrictor often used in critical care settings, particularly for septic shock. Unlike many other vasoactive medications (like norepinephrine or dopamine), vasopressin is typically dosed in fixed units per minute rather than based on patient weight (mcg/kg/min).
To determine the correct IV pump setting (mL/hr), nurses and pharmacists use the following formula:
Rate (mL/hr) = (Desired Dose × 60) / Concentration
Where:
- Desired Dose: Measured in units/min (e.g., 0.03 or 0.04 units/min).
- 60: Conversion factor from minutes to hours.
- Concentration: Total Drug Units divided by Total Volume (mL).
Calculation Example
Consider a standard concentration used in many Intensive Care Units:
- Total Drug: 20 Units
- Total Volume: 100 mL Normal Saline
- Ordered Dose: 0.03 units/min
Step 1: Determine Concentration
20 Units / 100 mL = 0.2 Units/mL
Step 2: Calculate Rate
(0.03 units/min × 60 min/hr) / 0.2 units/mL
1.8 / 0.2 = 9 mL/hr
In this scenario, the infusion pump should be programmed to 9 mL/hr.
Clinical Context and Dosing
Vasopressin is frequently indicated for vasodilatory shock (e.g., septic shock) that remains hypotensive despite fluid resuscitation and catecholamines. The Surviving Sepsis Campaign guidelines often suggest adding vasopressin to norepinephrine to raise Mean Arterial Pressure (MAP) or to decrease the norepinephrine dosage.
Common Dosing Parameters:
- Starting Dose: Often 0.03 units/minute.
- Range: Typically 0.01 to 0.04 units/minute.
- Titration: Vasopressin is often not titrated in the same manner as norepinephrine; it is frequently started at a fixed dose and discontinued when shock resolves, though protocols vary by institution.
Medical Disclaimer: This calculator is a tool for educational and double-checking purposes only. It should not replace professional medical judgment or institutional protocols. Always verify calculations and pump settings with a colleague or pharmacist before administering high-alert medications like Vasopressin.